The Same Dose Is Not For Everyone (Each Person Is Unique).
Genes determine the composition of all proteins of the body, and as medicines enter the body, they interact a lot with those proteins. Small but normal variations in your genes can produce proteins that work differently from their friends or relatives. This can affect how you react — or do not react — to different kinds of medicines For example, certain pain relievers they only work when the body's proteins convert them in a way inactive to active. It varies considerably from person to person how well these proteins work. Another example, very small genetic differences can change how medicines called statins work to lower blood pressure cholesterol levels in the blood. Discovering the differences of the genetic makeup of people, will help doctors prescribe medicine and correct amounts for each person, making medicines more effective. The result will be the prevention of unnecessary effects, which "One dose for all" is commonly given today. An advantage of this type of research will be a better understanding of the genes that cause or contribute to diseases such as cancer, heart disease, diabetes, depression, and asthma. Pharmacogenetic investigations also help scientists figure out new and better ways to develop the medicines of the future.
A Resource for Research.
To understand better how people have different reactions to medicines, scientists conducting pharmacogenetic research need to find the normal variations between certain human genes. This can be done when collects DNA from blood samples or cells inside the cheek (mouth). Scientists store information from DNA samples in a research data library. To protect the privacy of study volunteers, researchers will not name individuals or other personal information along with DNA information Registered in the Research Data Library.
Medicines for You.
Your lifestyle, the foods you eat, and where you live and works can totally affect how you react to medicines. But their genes may also contribute. Scientists study how your genes, Contained in your DNA, they influence your reaction to medicines. This type of Research is called pharmacogenetics or pharmacogenomics. In the last years, scientists have found genetic variations in people that affect reactions to: medicines that lower levels of cholesterol, cancer treatments, AIDS medicines, and many others commonly used drugs. In time, these investigations will provide information to guide your doctor in prescribing medicine and dosage correct for what your body needs.
Did you know that?• Some people do not get pain relief from certain prescription pain relievers.
You can find more information about the medicines and the safety of medicines on the Internet pages of the National Library
of Medicine, MedlinePlus: http://www.nlm.nih.gov/medlineplus/medicines.html